{"id":4412,"date":"2023-05-17T11:24:37","date_gmt":"2023-05-17T11:24:37","guid":{"rendered":"https:\/\/www.value-dx.eu\/?p=4412"},"modified":"2023-05-17T11:26:36","modified_gmt":"2023-05-17T11:26:36","slug":"value-dx-real-time-inclusions","status":"publish","type":"post","link":"https:\/\/www.value-dx.eu\/index.php\/2023\/05\/17\/value-dx-real-time-inclusions\/","title":{"rendered":"VALUE-Dx real-time inclusions"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-jzkylawd-ba86e75d702405f62001a756eb35483d\">\n.avia-section.av-jzkylawd-ba86e75d702405f62001a756eb35483d{\nbackground-color:#08b4a0;\nbackground-image:unset;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-jzkylawd-ba86e75d702405f62001a756eb35483d main_color avia-section-default avia-no-border-styling  avia-builder-el-0  el_before_av_section  avia-builder-el-first  avia-bg-style-parallax container_wrap fullsize'  ><div class='container av-section-cont-open' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-4412'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-kx4q0z2f-75f2aa2365a6f824cd5d33b5d04f7973\">\n#top .av-special-heading.av-kx4q0z2f-75f2aa2365a6f824cd5d33b5d04f7973{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-kx4q0z2f-75f2aa2365a6f824cd5d33b5d04f7973 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-kx4q0z2f-75f2aa2365a6f824cd5d33b5d04f7973 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-kx4q0z2f-75f2aa2365a6f824cd5d33b5d04f7973 av-special-heading-h3 blockquote modern-quote modern-centered  avia-builder-el-1  el_before_av_codeblock  avia-builder-el-first  av-linked-heading'><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >VALUE-Dx real-time inclusions<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1cjng-9db903d36b325f87b66fb9ba7e96614e\">\n.avia-section.av-1cjng-9db903d36b325f87b66fb9ba7e96614e{\nbackground-color:#1b7ca4;\nbackground-image:unset;\n}\n<\/style>\n<div id='av_section_2'  class='avia-section av-1cjng-9db903d36b325f87b66fb9ba7e96614e main_color avia-section-default avia-no-border-styling  avia-builder-el-3  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap fullsize'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-4412'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-k0i4yzrj-318dd765ad6f41d2fe86b741f8548ed0\">\n.flex_column.av-k0i4yzrj-318dd765ad6f41d2fe86b741f8548ed0{\nborder-radius:0px 0px 0px 0px;\npadding:50px 5% 50px 5%;\n}\n<\/style>\n<div  class='flex_column av-k0i4yzrj-318dd765ad6f41d2fe86b741f8548ed0 av_one_full  avia-builder-el-4  el_before_av_one_fifth  avia-builder-el-first  first flex_column_div  '     ><section  class='av_textblock_section av-yfjs-0595a18bcfdbd89cc5b7d6a0826f248c '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p><span style=\"font-weight: 400;\">Recently, two real-time graphs were added to the <\/span><a href=\"https:\/\/www.value-dx.eu\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">VALUE-Dx website<\/span><\/a><span style=\"font-weight: 400;\">, as an easy tool to track the inclusion progress of the PRUDENCE and ADEQUATE trails. This information is crucial because at the start of these trials, a target number of patients was set that has to be included for the trials to have statistical \u201cpower\u201d. If these targets aren\u2019t met, there is a risk that the studies will be considered unsuccessful because the research questions couldn\u2019t be answered with enough certainty.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The graphs are updated on a daily basis and show how many patients are recruited per site or per country. Thanks to this data, it becomes clear which sites or countries are recruiting well and which are lagging behind the inclusion schedule. These sites or countries are then approached to see how they can be supported in order to reach the target.\u00a0<\/span><\/p>\n<p><b>PRUDENCE (Primary Care)<\/b><b><br \/>\n<\/b><\/p>\n<p><span style=\"font-weight: 400;\">The PRUDENCE graph indicates the number of patients per setting and country. It is split up into patients in primary care and in long-term facility care. Within this trial, a country can have several sites, for example multiple GP offices in Primary Care.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/app.powerbi.com\/view?r=eyJrIjoiNmFlMDRlNzItZWJmYS00OWZhLTg4NDUtODY4MjMzMzVhMjNhIiwidCI6ImM2NDExNDM1LTJjMWYtNGRhNy04MTM1LTI3MjJhY2U4MGM0OSIsImMiOjh9\" target=\"_blank\" rel=\"noopener\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-4413\" src=\"https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-300x150.png\" alt=\"\" width=\"500\" height=\"250\" srcset=\"https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-300x150.png 300w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-1030x515.png 1030w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-768x384.png 768w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-1536x768.png 1536w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-1500x750.png 1500w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph-705x353.png 705w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/PRUDENCE-graph.png 1712w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<p><b>ADEQUATE (Emergency Rooms)<\/b><\/p>\n<p><span style=\"font-weight: 400;\">The ADEQUATE graph is also split up into two parts, the left part shows the number of paediatric patients enrolled per site and the right one the total number.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/app.powerbi.com\/view?r=eyJrIjoiZGQ1Mjc3MGYtNTlhZS00MmZkLWJiZDItMDQ2MDI2NzE0NTBhIiwidCI6ImM2NDExNDM1LTJjMWYtNGRhNy04MTM1LTI3MjJhY2U4MGM0OSIsImMiOjh9 \" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"aligncenter wp-image-4414\" src=\"https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-300x166.png\" alt=\"\" width=\"500\" height=\"277\" srcset=\"https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-300x166.png 300w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-1030x571.png 1030w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-768x426.png 768w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-1536x852.png 1536w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-1500x832.png 1500w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph-705x391.png 705w, https:\/\/www.value-dx.eu\/wp-content\/uploads\/2023\/05\/ADEQUATE-graph.png 1560w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">The inclusion graphs have been created by the VALUE-Dx Data Management &amp; Analytics team at the UMC Utrecht. The inclusion graphs are just one example of the team\u2019s output. Other graphs are crucial tools to monitor data quality and the data cleaning process.\u00a0<\/span><\/p>\n<p><b>About the trials<\/b><\/p>\n<p><span style=\"font-weight: 400;\">The PRUDENCE trial researches whether having a community-acquired acute respiratory tract infections diagnostic (CA-ARTI-Dx) test result available when a clinician is considering, or plans to prescribe an antimicrobial, leads to more appropriate prescribing decisions, without causing harm to patients.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The ADEQUATE trial is a randomised controlled trial of rapid syndromic diagnostic testing for enhancing the quality of antibiotic prescribing for community acquired acute respiratory tract infection (CA-ARTI) in emergency rooms in Europe.<\/span><\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" 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